Evgeniy Eruslanov

Company: University of Pennsylvania

Job title: Associate Professor

Bio:

Evgeniy Eruslanov, PhD, is a Research Associate Professor in the Department of Surgery at the Perelman School of Medicine, University of Pennsylvania. He completed postdoctoral training at Harvard University and the University of Florida. Hia research centers on the role of the tumor microenvironment in cancer development, with a particular emphasis on the functional and regulatory roles of human tumor-associated neutrophils and macrophages in lung cancer. His work investigates how these myeloid cells modulate tumor-specific T cell responses, natural killer (NK) cell activity, and immune responses triggered by anti-tumor antibodies in patients with lung cancer.

Seminars:

The Dual Role of Human Tumor-Associated Macrophages in Modulating Anti-Tumor Immune Responses in Lung Cancer 9:30 am

TAMs do not conform to the classic M1/M2 classification, exhibiting a distinct and complex phenotype in human lung cancer TAMs are not purely suppressive; they exert a range of effects—both inhibitory and stimulatory, on tumor-specific T-cell responses TAM-derived PD-L1 plays a critical and nuanced role in modulating anti-tumor T-cell activity TAMs regulate NK cell responses…Read more

day: Conference Day Two