Leslie Nangle

Company: aTyr Pharma Inc.

Job title: Vice President, Research

Bio:

Dr. Leslie Nangle leads research efforts at aTyr Pharma, where since she has helped build a discovery platform focused on extracellular tRNA synthetases and immune modulation. Holding a PhD from The Scripps Research Institute under the mentorship of Dr. Paul Schimmel, she has authored over 75 publications and holds a robust IP portfolio. Her leadership has driven the development of aTyr’s lead program, ATYR1923, a therapeutic targeting Neuropilin-2 in inflammatory lung diseases.

Seminars:

Reprogramming the Monocyte-to-Macrophage Axis: Steering Cell Fate to Resolve Chronic Inflammation & Fibrosis 11:30 am

Modulating monocyte differentiation to favor anti-inflammatory macrophage phenotypes in chronic disease settings Targeting cell fate decisions to disrupt pro-fibrotic macrophage programming Therapeutic strategies for durable macrophage reprogramming in inflammation and fibrosisRead more

day: Conference Day Two