Shweta Joshi

Company: University of California San Diego

Job title: Principal Investigator & Assistant Professor

Bio:

Dr. Joshi leads a research program focused on deciphering how myeloid cells, especially macrophages and MDSCs, drive tumor immunity and how they can be reprogrammed to combat cancer. Her lab has identified key molecular targets, including the tyrosine kinase SYK, and is actively advancing translational strategies to rewire the tumor microenvironment.

Seminars:

Reprogramming Macrophages to Increase CD8+ Cell Activation, Taken into Clinical Trials 9:00 am

Explore mechanisms by which macrophage modulation enhances CD8⁺ T-cell priming and infiltration Present preclinical data demonstrating anti-tumor immunity through macrophage reprogramming Share translational insights and outcomes from early-phase clinical trialsRead more

day: Conference Day Two

Comparing & Contrasting the Different Myeloid Pathways for Functional Reprogramming to Identify Which Pathways are Better Targets 9:00 am

A comprehensive deep dive into the key molecular pathways, cell-surface receptors, intracellular regulators, and emerging targets involved in the reprogramming of myeloid cells. Rank different pathways by therapeutic potential, feasibility and safety, to ultimately improve and better identify functional reprogramming strategies. Review the major myeloid-targeted strategies being pursued to reprogram immune-suppressive cells (especially M2-like TAMs)…Read more

day: Pre-Conference Workshop Day